Facile Two‐Step Synthesis of Porous Antigen‐Loaded Degradable Polyelectrolyte Microspheres

Marijke Dierendonck, Stefaan De Koker, Claude Cuvelier, Johan Grooten, Chris Vervaet, Jean‐Paul Remon, Bruno G. De Geest

Angewandte Chemie International Edition · 2010 · 43 citations · 37 references

DOIFull text

Open access

Concepts

Abstract

Pore medicine: Porous antigen-loaded degradable polyelectrolyte microspheres are produced in a straightforward way providing high encapsulation efficiencies and efficient internalization by antigen-presenting cells. This system could find application as multilayer capsules in gene and drug delivery and for enzymatic microreactors.

References

37