Concepedia

A short step synthesis of optically active myo-inositol 1,3,4,5-tetraki(phosphate) and myo-inositol 1,4,5-tris(phosphate) from 1,3,5-tri-O-benzoyl-myo-inositol

Yutaka Watanabe, Takahiro Fujimoto, Tomoichi Shinohara, Shoichiro Ozaki

Journal of the Chemical Society Chemical Communications · 1991 · 31 citations · 8 references

DOI

Concepts

Abstract

A short and practial synthesis of myo-inositol 1,3,4,5-tetraki(phosphate) and myo-inositol 1,4,5-tris(phosphate) has been achieved by direct benzoylation of myo-inositol, enantioselective tartaroylation and removal of acyl protecting groups with Grignard reagents.

References

8

An efficient phosphorylation method using a new phosphitylating agent, 2-diethylamino-1,3,2-benzodioxaphosphepane

Yutaka Watanabe, Yasunobu Komoda, Katsumi Ebisuya et al. · Tetrahedron Letters · 1990 · 98 citations

, , +5

Microbial oxidation in synthesis: preparation of myo-inositol phosphates and related cyclitol derivatives from benzene

Steven V. Ley, Margarita Parra, Alison J. Redgrave et al. · Tetrahedron · 1990 · 86 citations

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Enantiospecific synthesis of D-myo-inositol 1,4,5-trisphosphate from (-)-quinic acid

John R. Falck, Pendri Yadagiri · The Journal of Organic Chemistry · 1989 · 41 citations

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Easy access of optically active myo-inositol derivatives by enantioselective acylation using a tartaric acid monoester

Yutaka Watanabe, Oka Akinori, Shimizu Yasushi et al. · Tetrahedron Letters · 1990 · 31 citations

, , +8

Total synthesis of myo-inositol polyphosphates from benzene via conduritol B derivatives

H. A. J. CARLESS, Kofi Busia · Tetrahedron Letters · 1990 · 30 citations

, , +7