Synthetic Communications · 2007 · 10 citations · 11 references
Life SciencesBiochemistryChemistryLipid BiochemistryMetabolismOrganic ChemistryFatty Acid BiosynthesisFatty Acid ChemistryFatty Acid MetabolismLipid BiosynthesisLipid ChemistryLipid MetabolismEicosanoid Metabolic EnzymesEicosapentaenoic AcidFatty AcidsLipoxygenase InhibitionLipoxygenase PathwayMarine Fatty AcidsPolyunsaturated Fatty Acid MetabolismUnsaturated Fatty Acids
Abstract Starting from (all‐Z)‐eicosa‐5,8,11,14,17‐pentaenoic acid (EPA) and (all‐Z)‐4,7,10,13,16,19‐docosahexaenoic acid (DHA), several polyunsaturated fatty acids, containing a sulfur atom either in the chain or in a thiophene ring, have been synthesized as potential inhibitors of lipoxygenases.
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COX-2 Inhibitory Effects of Naturally Occurring and Modified Fatty Acids
Therese Ringbom, Ulrika Huss, Åke Stenholm et al. · Journal of Natural Products · 2001 · 214 citations · Full text