The Arndt–Eistert Reaction in Peptide Chemistry: A Facile Access to Homopeptides

Abstract

By combination of an Arndt-Eistert reaction sequence and a peptide coupling, amino acids and peptides can be coupled with a second amino acid or a second peptide to give homopeptides, for example of type 1. This method has been employed to synthesize up to homohexapeptides.

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