Zinc‐Triggered Hydrogelation of a Self‐Assembling β‐Hairpin Peptide

Christopher M. Micklitsch, Patrick J. Knerr, Monica C. Branco, Radhika P. Nagarkar, Darrin J. Pochan, Joel P. Schneider

Angewandte Chemie International Edition · 2011 · 141 citations · 37 references

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Concepts

Abstract

Zinc-chronized gelling: Selective zinc-triggered hydrogel formation is realized by the self-assembly of a de novo designed peptide (see picture). A non-natural, zinc-binding aminocarboxylate residue is incorporated into the peptide and is used to trigger folding, assembly, and subsequent gelation. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

References

37