mTOR Inhibitors Suppress Homologous Recombination Repair and Synergize with PARP Inhibitors via Regulating SUV39H1 in BRCA-Proficient Triple-Negative Breast Cancer - Concepedia

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mTOR Inhibitors Suppress Homologous Recombination Repair and Synergize with PARP Inhibitors via Regulating SUV39H1 in BRCA-Proficient Triple-Negative Breast Cancer

DOI Full Paper Access

141

Citations

37

References

2015

Year

Wei Mo, Qingxin Liu, Curtis Chun-Jen Lin, Hui Dai, Yang Peng, Yulong Liang, Guang Peng, Funda Meric‐Bernstam, Gordon B. Mills, Kaiyi Li,

Clinical Cancer Research

Abstract

Collectively, these findings strongly suggest that combining mTOR inhibitors and PARP inhibitors would be an effective therapeutic approach to treat BRCA-proficient TNBC patients.

References

	Year	Citations

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