2009 · 16 citations · 20 references
EngineeringBiochemistryBiological Systems ModelingComputational BiologyMetabolismBioprocess DesignBioprocess ModelingComputational ModelingMetabolic Pathway AnalysisMetabolism ModelingBiochemical Reaction NetworksComputational Biology ModelsMetabolic Network SimulationPathway Modeling
This paper surveys the design of software tools for the Bio-PEPA process algebra. Bio-PEPA is a high-level language for modelling biological systems such as metabolic pathways and other biochemical reaction networks. Through providing tools for this modelling language we hope to allow easier use of a range of simulators and model-checkers thereby freeing the modeller from the responsibility of developing a custom simulator for the problem of interest. Further, by providing mappings to a range of different analysis tools the Bio-PEPA language allows modellers to compare analysis results which have been computed using independent numerical analysers, which enhances the reliability and robustness of the results computed. 1
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L. F. Shampine, Mark W. Reichelt · SIAM Journal on Scientific Computing · 1997 · 3.6K citations · Full text
Natural Sciences, Computer Science, Differential Equations +9
A.C. Hindmarsh, Peter N. Brown, Keith Eric Grant et al. · ACM Transactions on Mathematical Software · 2005 · 2.6K citations · Full text