Computer applications in the biosciences · 2005 · 3.1K citations · 20 references
Life SciencesBioinformaticsEvolutionary BiologyMolecular EvolutionPhylogeneticsSequence AnalysisEvolutionary Model SelectionModel Selection In PhylogeneticsPhylogenetic AnalysisPhylogenetic Tree ReconstructionProtein EvolutionProtein Sequence AnalysisAmino Acid ReplacementAmino Group ReplacementPhylogenetic Analysis Of ProteinsProtein Evolution ModelsProtein Sequence AlignmentProtein Sequence EvolutionSubstitution Model SelectionSubstitution Models
SUMMARY: Using an appropriate model of amino acid replacement is very important for the study of protein evolution and phylogenetic inference. We have built a tool for the selection of the best-fit model of evolution, among a set of candidate models, for a given protein sequence alignment. AVAILABILITY: ProtTest is available under the GNU license from http://darwin.uvigo.es
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A Mathematical Theory of Communication
Claude E. Shannon · Bell System Technical Journal · 1948 · 80.7K citations
MODELTEST: testing the model of DNA substitution.
David Posada, Keith A. Crandall · Bioinformatics · 1998 · 20.1K citations