Protein and Peptide Letters · 2008 · 16 citations · 0 references
Life SciencesBioinformaticsImmunologyStructural BioinformaticsVaccine ImmunologyVaccinologyPlant Immune ResponsesVaccine Antigen DiscoveryVaccine PlatformsB-cell Epitope DiscoveryB-cell EpitopesComputational Epitope PredictionPeptide Vaccine Antigen DiscoveryPlant Protein IdentificationPollen Allergen CharacterizationT-cell Epitope DiscoveryT-cell Epitopes
Plant profilins form a well-known panallergen family responsible for cross-sensitization between plant foods and pollens. We sought to map T and B-cell epitopes on the Iranian Crocus sativus profilin by bioinformatics tools. The predicted peptides are useful for further vaccine development. Keywords: Epitope, Profilin, Crocus sativus, Bioinformatics