Concepedia

Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons

Ruishan Wang, Jing Jing Li, Shiyong Diao, Young-Don Kwak, Li Liu, Lianteng Zhi, Hansruedi Büeler, Narayan R. Bhat, Robert W. Williams, Edwards A. Park,

Cell Metabolism · 2013 · 194 citations · 48 references

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48

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

Frédéric Picard, Martin V. Kurtev, Acharawan Topark‐Ngarm et al. · Nature · 2004 · 1.9K citations · Full text

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Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide

Enzo Nisoli, Emilio Clementi, Clara Paolucci et al. · Science · 2003 · 1.2K citations

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Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice

Jiandie D. Lin, Pei-Hsuan Wu, Paul T. Tarr et al. · Cell · 2004 · 1.2K citations · Full text

, , +16

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

Do‐Hoon Kim, Minh Dang Nguyen, Matthew M. Dobbin et al. · The EMBO Journal · 2007 · 1.1K citations · Full text

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Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration

Libin Cui, Hyunkyung Jeong, Fran Borovečki et al. · Cell · 2006 · 990 citations · Full text

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