FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION: I. PROBLEMS, METHODS, AND PREPARATION OF EXTRACT
The Journal of Experimental Medicine · 1946 · 278 citations · 4 references
Purification MethodHepatologyBiochemistryMedicineLiver PhysiologyBioanalysisHistopathologyTechnical ProceduresLarge ScaleLiver SuspensionsCell CultureNatural SciencesHepatotoxicityLiver DiseaseLiverPharmacologyBiomolecular EngineeringChromatography
1. Materials and technical procedures involved in the preparation of liver suspensions have been described and discussed. 2. Liver extracts prepared by the present method appear to contain almost exclusively elements of cytoplasmic origin and can be considered to represent, on a large scale, the cytoplasm of liver cells.
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FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION
Albert Claude · The Journal of Experimental Medicine · 1946
281 citations
The Constitution of Protoplasm
Albert Claude · Science · 1943
230 citations
THE CONSTITUTION OF MITOCHONDRIA AND MICROSOMES, AND THE DISTRIBUTION OF NUCLEIC ACID IN THE CYTOPLASM OF A LEUKEMIC CELL
Albert Claude · The Journal of Experimental Medicine · 1944
95 citations
ISOLATION OF CHROMATIN THREADS FROM THE RESTING NUCLEUS OF LEUKEMIC CELLS
Albert Claude, James S. Potter · The Journal of Experimental Medicine · 1943
71 citations