Cerebral Hypoperfusion Generates Cortical Watershed Microinfarcts in Alzheimer Disease

Abstract

In AD, cerebral hypoperfusion induces not only white matter changes but cortical watershed microinfarcts as well, further aggravating the degenerative process and worsening dementia. To prevent the formation of watershed cortical microinfarcts in AD, monitoring blood pressure and treating arterial hypotension are essential.