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High concentrations of phosphatidylinositol-4,5-bisphosphate may promote actin filament growth by three potential mechanisms: Inhibiting capping by neutrophil lysates, severing actin filaments and removing capping protein-β2 from barbed ends1This work was supported by Cooper Faculty Grant SPF 2821-94.1

High ConcentrationsProtein SecretionProtein FunctionSignal TransductionBiochemistryActin Filament GrowthNatural SciencesCytoskeletonCell MotilityCellular BiochemistryActin FilamentsMedicineCell BiologyCell SignalingCellular PhysiologyProtein Phosphorylation