Antiviral and Anti-Inflammatory Effects of Rosmarinic Acid in an Experimental Murine Model of Japanese Encephalitis

Vivek Swarup, Joydeep Ghosh, Soumya Ghosh, Amit Saxena, Anirban Basu

Antimicrobial Agents and Chemotherapy · 2007 · 257 citations · 14 references

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Abstract

Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

References

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