Paternity in Klinefelter's Syndrome—A Case Report

Abstract

A boy diagnosed to have Klinefelter's syndrome (KS) with a karyotype of 47XXY, at the age of 12 years underwent normal puberty and at age 17 years had a testicular volume of 10 ml. At age 22 he married and fathered a normal child. His paternity was proven by HLA typing of the parents and child. It is suggested that testosterone therapy in KS be given only when testicular failure has been definitely established.