New Flavanones from the Leaves of <i>Cryptocarya chinensis</i> and Their Antituberculosis Activity

Abstract

Abstract Four new flavanones, cryptoflavanones A–D ( 1 – 4 , resp.), together with eight known compounds, were isolated from the leaves of Cryptocarya chinensis. The structures of these new compounds were determined by spectral analyses. Among the isolated compounds, pinocembrin ( 5 ) and cryptocaryone ( 6 ) exhibited antituberculosis activity against Mycobacterium tuberculosis H 37 Rv strain in vitro with MIC values of 3.5 and 25.0 μg/ml, respectively.