Remarkably Stable Tetrahedral Intermediates: Carbinols from Nucleophilic Additions to<i>N</i>���Acylpyrroles

Abstract

Sufficiently stable intermediates formed in the reaction of N-acylpyrroles (1) with hydride and Grignard reagents can undergo further synthetic transformations and chromatographic purification to enable the generation of pyrrolecarbinols 2 in 76–95 % yields [Eq. (1)]. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2002/z19350_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.