Secretion of Secondary Metabolites by ATP-Binding Cassette Transporters in Plant Cell Suspension Cultures

Abstract

The substrate specificity of the yeast ( Saccharomyces cerevisiae ) pleiotropic drug resistance (PDR)-type ATP-binding cassette (ABC) transporters is extended to plant secondary metabolites of the tropane alkaloid family. Functional analysis of yeast PDR5 genes in transgenic tobacco ( Nicotiana