Synthesis, structures, and antimicrobial activity of nickel(II) and Zinc(II) complexes with 5-methoxy-2-[(3-methylaminopropylimino)methyl]phenol

Abstract

The Schiff base 5-methoxy-2-[(3-methylaminopropylimino)methyl]phenol (MMP) derived from 4-methoxysalicylaldehyde and N-methylpropane-1,3-diamine and its nickel(II) and zinc(II) complexes [Ni(MMP) 2 (NCS) 2 ] ( I ) and [ZnCl 2 (MMP)] ( II ), have been prepared and characterized by elemental analyses, IR, and single crystal X-ray crystallographic determination. The crystal of I is monoclinic: space group P 2 1 / c , a = 9.0488(8), b = 12.7768(12), c = 12.9232(11) Å, β = 101.927(5)°, V = 1461.9(2) Å 3 , Z = 2. The crystal of II is orthorhombic: space group Pbca , a = 11.6991(7), b = 13.2839(8), c = 20.4451(12) Å, V = 3177.4(3) Å 3 , Z = 8. The Schiff base coordinates to the metal atoms through the phenolate O and imine N atoms. The effect of these complexes on the antimicrobial activity against Staphylococcus aureus, Escherichia coli , and Candida albicans were studied.