BMJ · 1988 · 28 citations · 4 references
Life SciencesGeneticsPathologyHuman GeneticsImmunogeneticsMedical GeneticsGenetic DisordersHistocompatibilityInheritance PatternsMajor Histocompatibility ComplexCytotoxicity AssaysGenetic Disease MechanismsHla AllelesMechanismsRecessive Inheritance ModelsSibling Pair Analysis
thyrotoxicosis, two thirds of the affected sibling pairs shared both parental haplotypes. It was postulated that both parental haplotypes were important for the development of thyrotoxicosis. In other words the human leucocyte antigen gene contributing to the development of thyrotoxicosis may be inherited in a recessive fashion.'
4