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The multi-step phosphorelay mechanism of unorthodox two-component systems in E. coli realizes ultrasensitivity to stimuli while maintaining robustness to noises

Biophysical ModelingUnorthodox Two-component SystemsE. ColiNatural SciencesBiophysical AspectSynthetic BiologyMolecular BiologyMulti-step Phosphorelay MechanismProtein EngineeringBiological ComputingMolecular CommunicationBiophysics