Concepedia

Effects of Ketamine on Human UDP-Glucuronosyltransferases In Vitro Predict Potential Drug-Drug Interactions Arising from Ketamine Inhibition of Codeine and Morphine Glucuronidation

Verawan Uchaipichat, Pritsana Raungrut, Nuy Chau, Benjamas Janchawee, Allan M. Evans, John O. Miners

Drug Metabolism and Disposition · 2011 · 40 citations · 20 references

DOI

Concepts

References

20

HUMAN UDP-GLUCURONOSYLTRANSFERASES: ISOFORM SELECTIVITY AND KINETICS OF 4-METHYLUMBELLIFERONE AND 1-NAPHTHOL GLUCURONIDATION, EFFECTS OF ORGANIC SOLVENTS, AND INHIBITION BY DICLOFENAC AND PROBENECID

Verawan Uchaipichat, Peter I. Mackenzie, Xiao-Hui Guo et al. · Drug Metabolism and Disposition · 2004 · 334 citations

, , +14

PHARMACOKINETICS AND ANALGESIC EFFECT OF KETAMINE IN MAN

Judith A. Clements, W.S. Nimmo · British Journal of Anaesthesia · 1981 · 326 citations · Full text

, , +7

KETAMINE INFUSIONS: PHARMACOKINETICS AND CLINICAL EFFECTS

Jan Idvall, I. Ahlgren, K. F. Aronsen et al. · British Journal of Anaesthesia · 1979 · 310 citations · Full text

, , +11

Morphine Pharmacokinetics and Metabolism in Humans

Jan Hasselström, Juliette Säwe · Clinical Pharmacokinetics · 1993 · 276 citations

, , +10

The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and<i>in vitro–in vivo</i>extrapolation of drug clearance and drug-drug interaction potential

John O. Miners, Peter I. Mackenzie, Kathleen Knights · Drug Metabolism Reviews · 2009 · 226 citations

, , +17