Nuclear Import of αB-crystallin Is Phosphorylation-dependent and Hampered by Hyperphosphorylation of the Myopathy-related Mutant R120G

A missense mutation in the αB-crystallin chaperone gene causes a desmin-related myopathy

Patrick Vicart, Anne Caron, Pascale Guicheney et al. · Nature Genetics · 1998 · 1.1K citations

Genetic Disorder, Genetics, Missense Mutation +6

A novel nuclear structure containing the survival of motor neurons protein.

Q Liu, Gideon Dreyfuss · The EMBO Journal · 1996 · 766 citations · Full text

Molecular Neuroscience, Motor Neurons, Novel Nuclear Structure +8

Associations between distinct pre-mRNA splicing components and the cell nucleus.

David L. Spector, Xiang‐Dong Fu, Tom Maniatis · The EMBO Journal · 1991 · 535 citations · Full text

Transcriptional Regulation, Cell Nucleus, Genetics +7

Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

Michael P. Bova, Orna Yaron, Qingling Huang et al. · Proceedings of the National Academy of Sciences · 1999 · 367 citations · Full text

Protein Assembly, Genetics, Molecular Biology +17

The Small Heat Shock Protein αB-Crystallin Negatively Regulates Cytochrome c- and Caspase-8-dependent Activation of Caspase-3 by Inhibiting Its Autoproteolytic Maturation

Merideth C. Kamradt, Feng Chen, Vincent L. Cryns · Journal of Biological Chemistry · 2001 · 352 citations · Full text