Effect of i.v. ketamine in combination with epidural bupivacaine or epidural morphine on postoperative pain and wound tenderness after renal surgery

The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

Clifford J. Woolf · Pain · 1991 · 2K citations

Life Sciences, Neurobiology, Neuroscience +17

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

Nabil A. Anis, Stephen C. Berry, N.R. Burton et al. · British Journal of Pharmacology · 1983 · 1.4K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation.

Anthony H. Dickenson, Ann F. Sullivan · Neuropharmacology · 1987 · 839 citations

Life Sciences, Neurobiology, Neuroscience +16

Evidence for involvement ofN-methylaspartate receptors in ‘wind-up’ of class 2 neurones in the dorsal horn of the rat

Stephen N. Davies, David Lodge · Brain Research · 1987 · 666 citations

Life Sciences, Neurobiology, Neuroscience +16

Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery

Audun Stubhaug, Harald Breivik, Per Kristian Eide et al. · Acta Anaesthesiologica Scandinavica · 1997 · 516 citations

Nursing, Anesthesiology, Surgery +17