Protein S–K196E mutation as a genetic risk factor for deep vein thrombosis in Japanese patients

Abstract

Deep vein thrombosis (DVT) is a multifactorial disease caused by interactions between acquired risk factors and coagulation abnormalities.[1][1] In whites, the factor V–Leiden and the prothrombin-20210G>A are widely recognized as genetic risk factors for DVT. However, these 2 mutations are not