Short-Term Tropisetron Treatment and Cognitive and P50 Auditory Gating Deficits in Schizophrenia

Abstract

The improvement of cognition with tropisetron appeared to be associated with normalization in P50 deficits. Thus, α7 nAChR agonists appear to be a promising therapeutic approach for the treatment of cognitive deficits that are related to abnormal P50 suppression in schizophrenia.