Concepedia

A Spätzle-Processing Enzyme Required for Toll Signaling Activation in Drosophila Innate Immunity

In-Hwan Jang, Naoyuki Chosa, Sunghee Kim, Hyuck-Jin Nam, Bruno Lemaître, Masanori Ochiai, Zakaria Kambris, Sylvain Brun, Carl Hashimoto, Masaaki Ashida,

Developmental Cell · 2006 · 308 citations · 48 references

Open access

Concepts

Life SciencesEntomologyImmunologyInnate ImmunityInsect ImmunologySignal TransductionInnate Immune ActivationInnate Immune ReceptorsInnate Immune ResponseInnate Immune Signaling PathwaysInvertebrate ImmunityToll-like ReceptorsToll-like Receptor LigandsToll-like Receptor SignalingToll-like Receptor Signaling CascadesToll-like Receptor Signaling Pathway GeneticsToll-like Receptor Signaling PathwaysToll-like Receptor-mediated Cytokine InductionToll-like Receptor-mediated Innate Immune Response

References

48

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Bruno Lemaître, Émmanuelle Nicolas, Lydia Michaut et al. · Cell · 1996 · 4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Genetic Transformation of <i>Drosophila</i> with Transposable Element Vectors

Gerald M. Rubin, Allan C. Spradling · Science · 1982 · 3K citations

Life Sciences, Genetics, Molecular Genetics +17

Drosophila — A Practical Approach

Biochemical Education · 1987 · 1.8K citations

Life Sciences, Biology, Entomology +5

The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

Carl Hashimoto, Kathy Hudson, Kathryn V. Anderson · Cell · 1988 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +16

The Toll and Imd pathways are the major regulators of the immune response in Drosophila

Ennio De Gregorio, Paul T. Spellman, Phoebe Tzou et al. · The EMBO Journal · 2002 · 959 citations · Full text

Life Sciences, Entomology, Immunology +16