Concepedia

A Tumorigenic Factor Interactome Connected through Tumor Suppressor MicroRNA-198 in Human Pancreatic Cancer

Christian Marín‐Müller, Dali Li, Uddalak Bharadwaj, Min Li, Changyi Chen, Sally E. Hodges, William E. Fisher, Qianxing Mo, Mien‐Chie Hung, Qizhi Yao

Clinical Cancer Research · 2013 · 83 citations · 34 references

DOIFull text

Open access

Abstract

miR-198 acts as a central tumor suppressor and modulates the molecular makeup of a critical interactome in pancreatic cancer, indicating a potential prognostic marker signature and the therapeutic potential of attacking this tumorigenic network through a central vantage point.

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