Concepedia

Topical Cyclosporine in Thyroid Orbitopathy-Related Dry Eye: Clinical Findings, Conjunctival Epithelial Apoptosis, and MMP-9 Expression

Canan Gürdal, İpek Genç, Özge Saraç, İpek Işık Gönül, Tamer Takmaz, İzzet Can

Current Eye Research · 2010 · 66 citations · 24 references

DOI

Abstract

Topical CsA treatment appears to improve the signs and symptoms of dry eye and inhibits apoptosis and MMP-9 expression in conjunctival epithelial cells in TO-related dry eye patients after 2 months of treatment.

References

24

Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca

Stephen C. Pflugfelder, David Jones, Zhonghua Ji et al. · Current Eye Research · 1999 · 608 citations

Experimental Dry Eye Stimulates Production of Inflammatory Cytokines and MMP-9 and Activates MAPK Signaling Pathways on the Ocular Surface

Lihui Luo, De‐Quan Li, Amish Doshi et al. · Investigative Ophthalmology & Visual Science · 2004 · 578 citations

Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye

Cintia S. de Paiva, Rosa M. Corrales, Arturo Villarreal et al. · Experimental Eye Research · 2006 · 440 citations

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Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis

Naoufal Zamzami, Philippe Marchetti, Maria Castedo et al. · FEBS Letters · 1996 · 439 citations · Full text

Analysis of Inflammatory Cytokines in the Tears of Dry Eye Patients

M. L. Massingale, Xiaohong Li, M. Vallabhajosyula et al. · Cornea · 2009 · 406 citations