Contribution of Homeostatic Chemokines CCL19 and CCL21 and Their Receptor CCR7 to Coronary Artery Disease

Wenzhi Cai, Jie Tao, Xiaolin Zhang, Xiaoxiang Tian, Tengfei Liu, Xueyao Feng, Jing Bai, Chenghui Yan, Yaling Han

Arteriosclerosis Thrombosis and Vascular Biology · 2014 · 46 citations · 22 references

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Abstract

CCL19/CCL21-CCR7 is a novel homeostatic chemokine system that modulates human monocyte adhesion and migration, promoting atherogenesis. It is associated with coronary artery disease risk in Chinese Han individuals. These data suggest that the CCL19/CCL21-CCR7 axis plays an important role in atherosclerosis progression.

References

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