Concepedia

Glial cell line-derived neurotrophic factor is constitutively produced by human testicular peritubular cells and may contribute to the spermatogonial stem cell niche in man

Katrin Spinnler, F.‐M. Köhn, U. Schwarzer, Artur Mayerhofer

Human Reproduction · 2010 · 101 citations · 26 references

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Abstract

Peritubular cells in testes of normal and sub-/infertile men produce GDNF and are likely constitutive contributors of the SSC niche in the human testis.

References

26

Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF

Xiaojuan Meng, Maria Lindahl, Mervi E. Hyvönen et al. · Science · 2000 · 1.4K citations

Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells

Hiroshi Kubota, Mary R. Avarbock, Ralph L. Brinster · Proceedings of the National Academy of Sciences · 2004 · 975 citations · Full text

A Vasculature-Associated Niche for Undifferentiated Spermatogonia in the Mouse Testis

Shosei Yoshida, Mamiko Sukeno, Yo‐ichi Nabeshima · Science · 2007 · 479 citations

, , +21

Glial Cell-Line Derived Neurotrophic Factor-Mediated RET Signaling Regulates Spermatogonial Stem Cell Fate1

C.K. Naughton, Sanjay Jain, Amy Strickland et al. · Biology of Reproduction · 2005 · 388 citations

Homeostatic regulation of germinal stem cell proliferation by the GDNF/FSH pathway

Yuko Tadokoro, Kentaro Yomogida, Hiroshi Ohta et al. · Mechanisms of Development · 2002 · 302 citations

, , +10