American journal of diseases of children · 1968 · 164 citations · 21 references
Pediatric OtolaryngologyAntibioticsPathogenesisHealthcare-associated InfectionOtolaryngologyOtorhinolaryngologyVirologyAcute Otitis MediaMicrobiologyInfection ControlMiddle Ear FluidClinical Infectious DiseaseMedicineClinical MicrobiologyHearing Loss
ACUTE otitis media is a common problem in infants and children. Although antibiotics seem to be effective in controlling suppurative complications, otitis is still a significant cause of morbidity and hearing loss. The etiology remains unsettled and treatment is largely empirical. Bacteriologic studies have repeatedly demonstrated that in only 60% to 70% of cases is it possible to isolate a pathogen from middle ear fluid.<sup>1-5</sup>Unproved explanations for the sterility of the remaining 30% to 40% are diverse and include a possible viral etiology.<sup>5</sup>There have been only sporadic accounts of virus isolation from middle ear fluid; few systematic attempts to isolate virus from middle ear fluid have been reported.<sup>5-8</sup>The association of<i>Mycoplasma</i>with bullous myringitis has been observed in adult volunteers infected with artificially propagated<i>M pneumoniae</i>.<sup>9</sup>In naturally acquired<i>M</i><i>pneumoniae</i>infection the organism has been recovered on several occasions from the middle
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OTITIS MEDIA IN THE PRACTICE OF PEDIATRICS
John D. Coffey · PEDIATRICS · 1966 · 140 citations
Pathogenic Microbiology, Pediatric Audiology, Otorhinolaryngology +18