Concepedia
Gut · 2014 · 147 citations · 40 references
Open access
Hypoxia decreases hepatic hepcidin expression by a novel regulatory pathway exerted via PDGF-BB, leading to increased availability of circulating iron that can be used for erythropoiesis.
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Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science · 2004 · 4.7K citations
Iron Metabolism, Immunology, Molecular Biology +20
A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload
Christelle Pigeon, Gennady P. Ilyin, Brice Courselaud et al. · Journal of Biological Chemistry · 2001 · 1.7K citations · Full text
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
Gaël Nicolas, Caroline Chauvet, Lydie Viatte et al. · Journal of Clinical Investigation · 2002 · 1.4K citations · Full text
Iron Metabolism, Immunology, Iron Deficiency +19
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 ( <i>USF2</i> ) knockout mice
Gaël Nicolas, Myriam Bennoun, Isabelle Devaux et al. · Proceedings of the National Academy of Sciences · 2001 · 1.2K citations · Full text
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
Jodie L. Babitt, Franklin W. Huang, Diedra M. Wrighting et al. · Nature Genetics · 2006 · 1K citations
Sclerostin, Signal Transduction, Bone Morphogenic Protein +6