Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB - Concepedia

Concepedia

Publication | Open Access

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

DOI Full Paper Access

147

Citations

40

References

2014

Year

Thomas Sonnweber, David Nachbaur, Andrea Schroll, Manfred Nairz, Markus Seifert, Egon Demetz, David Haschka, Anna‐Maria Mitterstiller, Axel Kleinsasser, Martin Burtscher,

Abstract

Hypoxia decreases hepatic hepcidin expression by a novel regulatory pathway exerted via PDGF-BB, leading to increased availability of circulating iron that can be used for erythropoiesis.

References

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