Concepedia

Nuclear and cytoplasmic maturation of in vitro matured human oocytes after temporary nuclear arrest by phosphodiesterase 3-inhibitor

Leen Vanhoutte, Petra De Sutter, Daniela Nogueira, Jan Gerris, Marc Dhont, Josiane Van Der Elst

Human Reproduction · 2007 · 97 citations · 41 references

DOIFull text

Open access

Abstract

Temporary nuclear arrest of human GV oocytes with PDE3-I proved to be beneficial for obtaining normal spindle and chromosome configurations after IVM. It resulted also in synchronization within the population of GV oocytes.

References

41

THE COMPARATIVE BEHAVIOR OF MAMMALIAN EGGS IN VIVO AND IN VITRO

Gregory Pincus, E. V. Enzmann · The Journal of Experimental Medicine · 1935 · 990 citations · Full text

, , +21

Maturation in vitro of Mouse, Sheep, Cow, Pig, Rhesus Monkey and Human Ovarian Oocytes

R. G. Edwards · Nature · 1965 · 834 citations

, , +13

Fertilization and early embryology: Influence of maternal age on meiotic spindle assembly oocytes from naturally cycling women

David Battaglia, Paul C. Goodwin, Nathan Klein et al. · Human Reproduction · 1996 · 642 citations · Full text

Maturation and fertilization of morphologically immature human oocytes in a program of in vitro fertilization

Lucinda L. Veeck, J.W. Edward Wortham, J. Witmyer et al. · Fertility and Sterility · 1983 · 376 citations

, , +15

Transcriptional Activity of the Mouse Oocyte Genome: Companion Granulosa Cells Modulate Transcription and Chromatin Remodeling

Rabindranath De La Fuente, John J. Eppig · Developmental Biology · 2001 · 373 citations

, , +8