Concepedia

Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agents

Ying-Qian Liu, Wei Dai, Chih-Ya Wang, Susan L. Morris‐Natschke, Xing-Wen Zhou, Yang Liu, Xiao-Ming Yang, Wen-Qun Li, Kuo‐Hsiung Lee

Bioorganic & Medicinal Chemistry Letters · 2012 · 14 citations · 10 references

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10

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.7K citations

Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA

Matthew R. Redinbo, Lance Stewart, Peter Kühn et al. · Science · 1998 · 874 citations

Camptothecin and Taxol:  Historic Achievements in Natural Products Research

Nicholas H. Oberlies, David J. Kroll · Journal of Natural Products · 2004 · 346 citations

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Molecular Modeling Studies of the DNA−Topoisomerase I Ternary Cleavable Complex with Camptothecin

Yi Fan, John N. Weinstein, Kurt W. Kohn et al. · Journal of Medicinal Chemistry · 1998 · 173 citations

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Quantitative Structure-Antitumor Activity Relationships of Camptothecin Analogues:  Cluster Analysis and Genetic Algorithm-Based Studies

Yi Fan, Leming Shi, Kurt W. Kohn et al. · Journal of Medicinal Chemistry · 2001 · 160 citations