Concepedia

The fibrinogen cleavage product A -Val360, a specific marker of neutrophil elastase activity in vivo

Richard I. Carter, Richard A. Mumford, Kelly Treonze, Paul E. Finke, Philip R. Davies, Qin Si, John L. Humes, Asger Dirksen, Eeva Piitulainen, Arsalan Ahmad,

Thorax · 2011 · 66 citations · 27 references

DOIFull text

Open access

Abstract

The EXACTLE study was registered in ClinicalTrials.gov as 'Antitrypsin (AAT) to Treat Emphysema in AAT-Deficient Patients'; ClinicalTrials.gov Identifier: NCT00263887.

References

27

Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease

Gavin C. Donaldson · Thorax · 2002 · 2.3K citations · Full text

A 4-Year Trial of Tiotropium in Chronic Obstructive Pulmonary Disease

Donald P. Tashkin, Bartolomé R. Celli, Stephen Senn et al. · New England Journal of Medicine · 2008 · 2.2K citations · Full text

A Randomized Clinical Trial of α <sub>1</sub> -Antitrypsin Augmentation Therapy

Asger Dirksen, Joop H. Dijkman, Flemming Madsen et al. · American Journal of Respiratory and Critical Care Medicine · 1999 · 494 citations

Survival and FEV <sub>1</sub> Decline in Individuals with Severe Deficiency of α <sub>1</sub> -Antitrypsin

American Journal of Respiratory and Critical Care Medicine · 1998 · 433 citations

Exploring the role of CT densitometry: a randomised study of augmentation therapy in α<sub>1</sub>-antitrypsin deficiency

Asger Dirksen, Eeva Piitulainen, David Parr et al. · European Respiratory Journal · 2009 · 345 citations · Full text