Translationally Controlled Tumor Protein Induces Mitotic Defects and Chromosome Missegregation in Hepatocellular Carcinoma Development - Concepedia

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Translationally Controlled Tumor Protein Induces Mitotic Defects and Chromosome Missegregation in Hepatocellular Carcinoma Development

79

Citations

28

References

2011

Year

Tim Hon Man Chan, Leilei Chen, Ming Liu, Liang Hu, Bo-Jian Zheng, Vincent Kwok‐Man Poon, Pinzhu Huang, Yunfei Yuan, Jian‐Dong Huang, Jie Yang,

Abstract

Collectively, we reveal a novel molecular pathway (CHD1L/TCTP/Cdc25C/Cdk1), which causes the malignant transformation of hepatocytes with the phenotypes of accelerated mitotic progression and the production of aneuploidy.

References

	Year	Citations
Global cancer statistics Ahmedin Jemal, Freddie Bray CA A Cancer Journal for Clinicians	2011	55K
Global Cancer Statistics, 2002 Donald Maxwell Parkin, Freddie Bray, Jacques Ferlay, CA A Cancer Journal for Clinicians Epidemiology Of CancerWorldwide IncidenceCancer RegistrationCancer DeathCancer Risk Factors	2005	18.4K
Matlnd and Matlnspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data Kerstin Quandt, Kornelie Frech, Holger Karas, Nucleic Acids Research	1995	2.6K
MatInspector and beyond: promoter analysis based on transcription factor binding sites Kerstin Cartharius, Kornelie Frech, Korbinian Grote, Computer applications in the biosciences	2005	1.9K
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers Scott L. Carter, Aron C. Eklund, Isaac S. Kohane, Nature Genetics ChromatinGenome InstabilityMultiple Human CancersTumor HeterogeneityChromosomal Instability	2006	1.2K
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1 Lyubomir T. Vassilev, Christian Tovar, Shaoqing Chen, Proceedings of the National Academy of Sciences Cdk1 InhibitionImmunologyHuman Cdk1Cell DeathCell Cycle	2006	804
Temporal and spatial control of cyclin B1 destruction in metaphase Paul Clute, Jonathon Pines Nature Cell Biology Signal TransductionBiochemistryNatural SciencesCell DeathCyclin B1 Destruction	1999	707
Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis. Ingrid Hoffmann, Paul R. Clarke, María Jesús Marcote, The EMBO Journal Signal TransductionSignaling PathwayCell DivisionCell RegulationMedicine	1993	674
Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase. Tetsuro Izumi, James L. Maller Molecular Biology of the Cell Cdc2 Phosphorylation SitesSignal TransductionCell RegulationCell DivisionMolecular Pathway	1993	289
Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. Stephan J. Sigrist, Henning W. Jacobs, R. Stratmann, The EMBO Journal BiologyChromatinCyclins ACell DivisionCell Control	1995	288

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