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Elevated Glutathione Levels Confer Cellular Sensitization to Cisplatin Toxicity by Up-Regulation of Copper Transporter hCtr1

Helen Chen, Im‐Sook Song, Anwar Hossain, Min‐Koo Choi, Y Yamane, Liang Zheng, Jia Lu, Lily Y. H. Wu, Zahid H. Siddik, Leo W. J. Klomp,

Molecular Pharmacology · 2008 · 79 citations · 22 references

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Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide Dismutase

Tracey Rae, Paul J. Schmidt, Robert A. Pufahl et al. · Science · 1999 · 1.6K citations

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Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

Seiko Ishida, Jaekwon Lee, Dennis J. Thiele et al. · Proceedings of the National Academy of Sciences · 2002 · 909 citations · Full text

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

Susan P.C. Cole, Kathryn E. Sparks, Karen Fraser et al. · PubMed · 1994 · 773 citations

, , +18

The Role of Glutathione in Copper Metabolism and Toxicity

Jonathan H. Freedman, Maria Rosa Ciriolo, J. Peisach · Journal of Biological Chemistry · 1989 · 587 citations · Full text

, , +13

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

Toshihisa Ishikawa, Francis Ali‐Osman · Journal of Biological Chemistry · 1993 · 536 citations · Full text