Association between<i>HLA‐B*4001</i>and Lipodystrophy among HIV‐Infected Patients from Thailand Who Received a Stavudine‐Containing Antiretroviral Regimen

Abstract

HLA-B*4001 is a strong genetic risk factor for stavudine-associated lipodystrophy in HIV-infected patients in Thailand. HLA-B*4001 may be used as a genetic marker to predict which patients will develop stavudine-associated lipodystrophy, to avoid or shorten the duration of stavudine use. This finding needs to be confirmed in further replication studies.