Correlations of in vitro and in vivo hepatotoxicity for five haloalkanes

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

Comparison of the biochemical alterations elicited in livers from rats treated with carbon tetrachloride, chloroform, 1,1,2-trichloroethaneand 1,1,1-trichloroethane

Curtis D. Klaassen, Gàbriel L. Plaa · Biochemical Pharmacology · 1969 · 207 citations

Hepatology, Biochemistry, Carbon Tetrachloride +13

Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: Role of cytochrome P-450

I.G. Sipes, Gopal Krishna, James R. Gillette · Life Sciences · 1977 · 197 citations

Engineering, Biochemistry, Environmental Engineering +8

Toxic Injury to Isolated Hepatocytes Is Not Dependent on Extracellular Calcium

Martyn T. Smith, Hjördis Thor, Sten Orrenius · Science · 1981 · 166 citations

Toxic Injury, Pathology, Cellular Physiology +22

A Structure-Activity Relationship of Some Chlorinated Hydrocarbons

Akio Sato, Tamie Nakajima · Archives of Environmental Health An International Journal · 1979 · 147 citations

Engineering, Air Quality, Exposure Assessment +20