Thyroid Hormone Induced Brown Adipose Tissue and Amelioration of Diabetes in a Patient with Extreme Insulin Resistance

Monica C. Skarulis, Francesco S. Celi, Elisabetta Mueller, Marina Zemskova, Rana Malek, Lynne Hugendubler, Craig Cochran, Jeffrey Solomon, Clara Chen, Phillip Görden

The Journal of Clinical Endocrinology & Metabolism · 2009 · 159 citations · 26 references

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Abstract

This case demonstrates the TH effect on BAT activity and volume in this patient and an association between BAT activity and glucose levels in this patient. Because the contribution of TH on skeletal muscle energy expenditure and fuel metabolism was not assessed, an association between BAT activity and glucose homeostasis can only be suggested.

References

26