Concepedia

Association of Serum Cytokine Levels With Treatment Response to Pegylated Interferon and Ribavirin Therapy in Genotype 1 Chronic Hepatitis C Patients

Suguru Yoneda, Takeji Umemura, Yoshihiko Katsuyama, Atsushi Kamijo, Satoru Joshita, Michiharu Komatsu, Tetsuya Ichijo, Akihiro Matsumoto, Kaname Yoshizawa, Masao Ôta,

The Journal of Infectious Diseases · 2011 · 55 citations · 40 references

DOIFull text

Open access

Abstract

Serum IL-10, IL-12, and IL-18 levels are predictive of the response to HCV treatment with pegylated interferon and ribavirin and are associated with amino acid substitutions in the ISDR and core region.

References

40

Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection

Michael Fried, Mitchell L. Shiffman, K. Rajender Reddy et al. · New England Journal of Medicine · 2002 · 6.4K citations

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

Michael P. Manns, John G. McHutchison, Stuart C. Gordon et al. · The Lancet · 2001 · 6K citations

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Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

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IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

David Fiorentino, Albert Zlotnik, Paulo Vieira et al. · The Journal of Immunology · 1991 · 1.9K citations · Full text

Detection of Antibody to Hepatitis C Virus in Prospectively Followed Transfusion Recipients with Acute and Chronic Non-A, Non-B Hepatitis

Harvey J. Alter, Robert H. Purcell, J W Shih et al. · New England Journal of Medicine · 1989 · 1.7K citations