Nitric oxide, superoxide and renal blood flow autoregulation in SHR after perinatal <scp>L</scp>‐arginine and antioxidants

Abstract

Perinatal supplements shifted RBF autoregulation characteristics of SHR towards WKY, although capacity of the SHRsuppl kidney to modulate NO production to shear stress still seems impaired. The less strictly controlled RBF as observed in perinatally supplemented SHR could result in an improved long-term blood pressure control. This might partly underlie the beneficial effects of perinatal supplementation.