Concepedia

Safety and efficacy of a xenogeneic DNA vaccine encoding for human tyrosinase as adjunctive treatment for oral malignant melanoma in dogs following surgical excision of the primary tumor

Deborah A. Grosenbaugh, A. Timothy Leard, Philip J. Bergman, Mary K. Klein, Karri A. Meleo, Steven Susaneck, Paul R. Hess, Monika K. Jankowski, Pamela D. Jones, Nicole F. Leibman,

American Journal of Veterinary Research · 2011 · 218 citations · 20 references

DOIFull text

Open access

Abstract

Response to DNA vaccination in dogs with oral MM may be useful in development of plasmid DNA vaccination protocols for human patients with similar disease.

References

20

Multi-center, Placebo-controlled, Double-blind, Randomized Study of Oral Toceranib Phosphate (SU11654), a Receptor Tyrosine Kinase Inhibitor, for the Treatment of Dogs with Recurrent (Either Local or Distant) Mast Cell Tumor Following Surgical Excision

Cheryl A. London, Phyllis B. Malpas, Stacey L. Wood-Follis et al. · Clinical Cancer Research · 2009 · 416 citations · Full text

Long-term survival of dogs with advanced malignant melanoma after DNA vaccination with xenogeneic human tyrosinase: a phase I trial.

Philip J. Bergman, J. A. McKnight, Andrew Novosad et al. · PubMed · 2003 · 331 citations

Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center

Philip J. Bergman, M. A. Camps‐Palau, J. A. McKnight et al. · Vaccine · 2005 · 291 citations

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Coupling and Uncoupling of Tumor Immunity and Autoimmunity

Wilbur B. Bowne, Roopa Srinivasan, Jedd D. Wolchok et al. · The Journal of Experimental Medicine · 1999 · 241 citations · Full text

Tumor immunity and autoimmunity induced by immunization with homologous DNA.

L W Weber, Wilbur B. Bowne, Jedd D. Wolchok et al. · Journal of Clinical Investigation · 1998 · 229 citations · Full text

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