4,5-Functionalized 6-phenyl-3(2H)-pyridazinones: synthesis and evaluation of antinociceptive activity

A Method for Evaluating both Non-Narcotic and Narcotic Analgesics

Estelle A. Siegmund, R. Cadmus, Gongxuan Lü · Experimental Biology and Medicine · 1957 · 491 citations

Pain Disorders, Pain Medicine, Pharmacotherapy +22

A new nonsteroidal analgesic-antiinflammatory agent. Synthesis and activity of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone and related compounds

M. TAKAYA, Maria Notomi Sato, K. Terashima et al. · Journal of Medicinal Chemistry · 1979 · 72 citations

Synthesis of Mannich Bases of Arylidenepyridazinones as Analgesic Agents

Catherine Rubat, Pascal Coudert, E Albuisson et al. · Journal of Pharmaceutical Sciences · 1992 · 45 citations

Medicinal Chemistry, Natural Sciences, Organic Chemistry +5

The analgetic properties of piroxicam in animals and correlation with expreimentally determined plasma levels

George M. Milne, Thomas M. Twomey · Inflammation Research · 1980 · 40 citations

Animal Physiology, Plasma Levels, Medicine +10

Novel nonopioid non-antiinflammatory analgesics: 3-(aminoalkyl)- and 3-[(4-aryl-1-piperazinyl)alkyl]oxazolo[4,5-b]pyridin-2(3H)-ones

Christine Flouzat, Y Bresson, Anny Mattio et al. · Journal of Medicinal Chemistry · 1993 · 36 citations