A micro-perfusion chamber for single-cell fluorescence measurements

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

Roger Y. Tsien, Tullio Pozzan, T J Rink · The Journal of Cell Biology · 1982 · 2.3K citations · Full text

Life Sciences, Biochemistry, Biophysics +13

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

Roger Y. Tsien, Tullio Pozzan, T J Rink · Nature · 1982 · 1K citations

Life Sciences, Cell Biology, Immunology +16

Haemodynamic shear stress activates a K+ current in vascular endothelial cells

Søren‐Peter Olesen, David E. Clapham, Peter F. Davies · Nature · 1988 · 1K citations

Medicine, Biophysics, Cell Biology +14

Measurement of cytosolic free Ca2+ in individual small cells using fluorescence microscopy with dual excitation wavelengths

Roger Y. Tsien, T J Rink, Martin Poenie · Cell Calcium · 1985 · 655 citations

Natural Sciences, Biophysics, Cell Biology +17