Cholesteryl ester hydrolase activity is abolished in HSL macrophages but unchanged in macrophages lacking KIAA1363

Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase

Guenter Haemmerle, Achim Lass, Robert Zimmermann et al. · Science · 2006 · 1.4K citations · Full text

Metabolic Syndrome, Energy Homeostasis, Biochemistry +12

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

S K Basu, J L Goldstein, Gary Anderson et al. · Proceedings of the National Academy of Sciences · 1976 · 1K citations · Full text

Low Density Lipoprotein, Metabolic Syndrome, Cholesterol Metabolism +15

The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.

Michael S. Brown, Y K Ho, Joseph L. Goldstein · Journal of Biological Chemistry · 1980 · 729 citations · Full text

Cholesteryl Ester Cycle, Biomanufacturing, Oxysterol +6

Hormone-sensitive Lipase Deficiency in Mice Causes Diglyceride Accumulation in Adipose Tissue, Muscle, and Testis

Guenter Haemmerle, Robert Zimmermann, Marianne Hayn et al. · Journal of Biological Chemistry · 2002 · 604 citations · Full text

Metabolic Disorder, Obesity, Metabolic Syndrome +17

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

Jun-ichi Osuga, Shun Ishibashi, Teruaki Oka et al. · Proceedings of the National Academy of Sciences · 2000 · 577 citations