Concepedia

Discovery of a new chemical lead for a matrix metalloproteinase inhibitor

Masahiro Ikura, Shingo Nakatani, Shingo Yamamoto, Hiromu Habashita, Tsuneyuki Sugiura, Kanji Takahashi, Koji Ogawa, Hiroyuki Ohno, Hisao Nakai, Masaaki Toda

Bioorganic & Medicinal Chemistry · 2006 · 12 citations · 5 references

DOI

Concepts

References

5

LUDI: rule-based automatic design of new substituents for enzyme inhibitor leads

Hans-Joachim B�hm · Journal of Computer-Aided Molecular Design · 1992 · 456 citations

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1.56 Å structure of mature truncated human fibroblast collagenase

John Spurlino, Angela Smallwood, Dennis Carlton et al. · Proteins Structure Function and Bioinformatics · 1994 · 185 citations

COMBINATION OF BORANE-DIMETHYL SULFIDE COMPLEX WITH CATALYTIC SODIUM TETRAHYDROBORATE AS A SELECTIVE REDUCING AGENT FOR α-HYDROXY ESTERS. VERSATILE CHIRAL BUILDING BLOCK FROM (<i>S</i>)-(−)-MALIC ACID

Seiki Saitô, Takashi Hasegawa, Masami Inaba et al. · Chemistry Letters · 1984 · 161 citations

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Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development

David G. Barrett · Drug Discovery Today · 2002 · 75 citations

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Novel matrix metalloproteinase inhibitors: Generation of lead compounds by the in silico fragment-based approach

Kanji Takahashi, Masahiro Ikura, Hiromu Habashita et al. · Bioorganic & Medicinal Chemistry · 2005 · 25 citations

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