Expression and prognostic relevance of Mcl-1 in breast cancer.

Lorraine O’Driscoll, Deirdre Cronin, Susan Kennedy, Rachel Purcell, Rasha Linehan, Sharon A. Glynn, A. Larkin, K Scanlon, E. McDermott, Amanda Hill,

PubMed · 2004 · 22 citations · 17 references

Abstract

As these analyses of mcl-1 expression may have co-detected mcl-1(S/deltaTM) (a more recently identified, shorter variant, that may be pro-apoptotic) with the anti-apoptotic wild-type of mcl-1, it is possible that future studies may indicate some significant clinical correlations if the isoforms can be independently investigated.

References

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