Hemodynamic Effects of Sildenafil in Patients With Congestive Heart Failure and Pulmonary Hypertension

Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial

Hossein Ardeschir Ghofrani, R. Wiedemann, Frank Rose et al. · The Lancet · 2002 · 769 citations

Pulmonary Arterial Hypertension, Antifibrotic Therapy, Pharmacology +10

Preserved right ventricular ejection fraction predicts exercise capacity and survival in advanced heart failure

Thomas G. Di Salvo, Michael Mathier, Marc J. Semigran et al. · Journal of the American College of Cardiology · 1995 · 681 citations

Heart Failure, Kinesiology, Cardiovascular Disease +9

Oral Sildenafil Is an Effective and Specific Pulmonary Vasodilator in Patients With Pulmonary Arterial Hypertension

Evangelos D. Michelakis, Wayne Tymchak, Dale Lien et al. · Circulation · 2002 · 577 citations · Full text

Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure

Wolfgang Kiowski, J Kim, Erwin Oechslin et al. · The Lancet · 1995 · 573 citations

Endothelin-1-mediated Vasoconstriction, Heart Failure, Cardiovascular Disease +7

Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro

Robert M. Wallis, Jackie D. Corbin, Sharron H. Francis et al. · The American Journal of Cardiology · 1999 · 509 citations

Medicine, Vascular Pharmacology, Physiology +6